Serpin E1/PAI-1 Monoklonaler Antikörper

Serpin E1/PAI-1 Monoklonal Antikörper für WB, IHC, IF/ICC, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

Hausschwein, human, Maus

Anwendung

WB, IHC, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

1H4A5

Kat-Nr. : 66261-1-PBS

Synonyme

PAI-1, SERPINE1, SERPINE1, PAI-1, 1H4A5, PAI



Geprüfte Anwendungen

Produktinformation

66261-1-PBS bindet in WB, IHC, IF/ICC, Indirect ELISA Serpin E1/PAI-1 und zeigt Reaktivität mit Hausschwein, human, Maus

Getestete Reaktivität Hausschwein, human, Maus
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen Serpin E1/PAI-1 fusion protein Ag22411
Vollständiger Name serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
Berechnetes Molekulargewicht 402 aa, 45 kDa
Beobachtetes Molekulargewicht45-50 kDa
GenBank-ZugangsnummerBC010860
Gene symbol PAI-1
Gene ID (NCBI) 5054
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SERPINE1, also named Plasminogen activator inhibitor type 1 (PAI-1), is a member of the serine protease inhibitor (SERPIN) superfamily. PAI-1 is the principal inhibitor of tissue plasminogen activator (tPA) and uPA, and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. The mature 379-residue protein had a calculated unglycosylated molecular mass of 42.7 kD. Three putative glycosylation sites were found.