Serpin E1/PAI-1 Monoklonaler Antikörper
Serpin E1/PAI-1 Monoklonal Antikörper für WB, IHC, IF/ICC, Indirect ELISA
Wirt / Isotyp
Maus / IgG1
Getestete Reaktivität
Hausschwein, human, Maus
Anwendung
WB, IHC, IF/ICC, Indirect ELISA
Konjugation
Unkonjugiert
CloneNo.
1H4A5
Kat-Nr. : 66261-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
66261-1-PBS bindet in WB, IHC, IF/ICC, Indirect ELISA Serpin E1/PAI-1 und zeigt Reaktivität mit Hausschwein, human, Maus
Getestete Reaktivität | Hausschwein, human, Maus |
Wirt / Isotyp | Maus / IgG1 |
Klonalität | Monoklonal |
Typ | Antikörper |
Immunogen | Serpin E1/PAI-1 fusion protein Ag22411 |
Vollständiger Name | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
Berechnetes Molekulargewicht | 402 aa, 45 kDa |
Beobachtetes Molekulargewicht | 45-50 kDa |
GenBank-Zugangsnummer | BC010860 |
Gene symbol | PAI-1 |
Gene ID (NCBI) | 5054 |
Konjugation | Unkonjugiert |
Form | Liquid |
Reinigungsmethode | Protein-G-Reinigung |
Lagerungspuffer | PBS only |
Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
SERPINE1, also named Plasminogen activator inhibitor type 1 (PAI-1), is a member of the serine protease inhibitor (SERPIN) superfamily. PAI-1 is the principal inhibitor of tissue plasminogen activator (tPA) and uPA, and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. The mature 379-residue protein had a calculated unglycosylated molecular mass of 42.7 kD. Three putative glycosylation sites were found.