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PAIP1 Monoklonaler Antikörper

PAIP1 Monoklonal Antikörper für ELISA

Wirt / Isotyp

Maus / IgG2b

Getestete Reaktivität

human, Maus

Anwendung

ELISA

Konjugation

Unkonjugiert

CloneNo.

2G1B7

Kat-Nr. : 60050-1-Ig

Synonyme

PABP interacting protein 1, PAIP 1, PAIP1

Galerie der Validierungsdaten

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  • Immunohistochemistry (IHC) staining of human cervical cancer tissue using PAIP1 Monoclonal antibody (60050-1-Ig)

    IHC staining of human cervical cancer using 60050-1-Ig

    Immunohistochemical analysis of paraffin-embedded human cervical cancer slide using 60050-1-Ig (PAIP1 Antibody) at dilution of 1:50.

Geprüfte Anwendungen

Empfohlene Verdünnung

AnwendungVerdünnung
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

60050-1-Ig bindet in ELISA PAIP1 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Maus / IgG2b
Klonalität Monoklonal
Typ Antikörper
Immunogen PAIP1 fusion protein Ag1070
Vollständiger Name poly(A) binding protein interacting protein 1
Berechnetes Molekulargewicht 70 kDa
Beobachtetes Molekulargewicht 42+60+70+110 kDa
GenBank-ZugangsnummerBC005295
Gene symbol PAIP1
Gene ID (NCBI) 10605
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
LagerungsbedingungenBei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

In initiation of translation in eukaryotes, binding of the small ribosomal subunit to mRNA requires recognition of the 5-prime cap structure by the cap-binding complex eIF4F. eIF4F consists of eIF4E, eIF4A, and eIF4G. Translation initiation is further regulated by the mRNA 3-prime poly(A) tail and the poly(A)-binding protein (PABC1). PAIP1 interacts with PABC1 and some eIF4 complexes [PMID:9548260]. It is a coactivator in the regulation of translation initiation of poly(A)-containing mRNAs, and associates with EIF4A and PABPC1 may potentiate contacts between mRNA termini [PMID:11051545].