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PAK3 Polyklonaler Antikörper

PAK3 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Hausschwein, human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 32848-1-PBS

Synonyme

Beta-PAK, EC:2.7.11.1, Oligophrenin-3, OPHN3, p21-activated kinase 3

Filter:
  • Western Blot (WB) analysis of various lysates using PAK3 Polyclonal antibody (32848-1-AP)

    WB analysis using 32848-1-AP (same clone as 32848-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 32848-1-AP (PAK3 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32848-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

32848-1-PBS bindet in WB, Indirect ELISA PAK3 und zeigt Reaktivität mit Hausschwein, human, Maus, Ratten

Getestete Reaktivität Hausschwein, human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen PAK3 fusion protein Ag38566
Vollständiger Name p21 protein (Cdc42/Rac)-activated kinase 3
Berechnetes Molekulargewicht62kDa，559aa
Beobachtetes Molekulargewicht64 kDa
GenBank-ZugangsnummerNM_001128173.2
Gene symbol PAK3
Gene ID (NCBI) 5063
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

PAK3, also known as p21-activated kinase 3, is a member of the PAK family of serine/threonine protein kinases, classified as Group I PAK kinases along with PAK1 and PAK2. PAK3 is predominantly expressed in neural cells, especially in regions such as the brain. PAK3 plays a crucial role in dendritic spine development and synaptic plasticity. PAK3 plays an important role in cell migration and morphology. It regulates dynamic changes in the actomyosin cytoskeleton, microtubules, and adhesion interactions with the microenvironment. In neurons and other cell types, PAK3 contributes to cell migration, neurite growth, and dendritic spine morphogenesis by participating in signaling cascades that control cell adhesion and cell motility. Mutations in PAK3 are associated with X-linked non-syndromic intellectual disability.