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PAK7 Polyklonaler Antikörper

PAK7 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 32085-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using PAK7 Polyclonal antibody (32085-1-AP)

    WB analysis using 32085-1-AP (same clone as 32085-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 32085-1-AP (PAK7 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32085-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

32085-1-PBS bindet in WB, Indirect ELISA PAK7 und zeigt Reaktivität mit human, Ratten

Getestete Reaktivität human, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen PAK7 fusion protein Ag29190
Vollständiger Name p21 protein (Cdc42/Rac)-activated kinase 7
Berechnetes Molekulargewicht 719 aa, 81 kDa
Beobachtetes Molekulargewicht80 kDa
GenBank-ZugangsnummerBC024179
Gene symbol PAK7
Gene ID (NCBI) 57144
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

PAK7, also known as PAK5, is a newly found but scarcely researched type II PAKs (PAK4, 5, 6). PAK7 was originally found in the brain, which promotes filopodia formation in nerve cells. Recently, studies have found that the expression level of PAK7 significantly increased in colorectal cancer, ovarian cancer, gastric cancer, neuroglioma, hepatocellular carcinoma, pancreatic cancer, osteosarcoma, and breast cancer. PAK7 plays an important role in tumorigenesis, invasion, and metastasis, mainly related to its mechanism of regulating cytoskeleton, inhibiting apoptosis, and promoting proliferation. The calculated molecular weight of PAK7 is 80 kDa (PMID: 29805709, PMID: 34165002).