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PANK4 Polyklonaler Antikörper

PANK4 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 32953-1-PBS

Synonyme

4'-phosphopantetheine phosphatase, EC:3.1.3.-, hPanK4, Inactive pantothenic acid kinase 4

Filter:
  • Western Blot (WB) analysis of various lysates using PANK4 Polyclonal antibody (32953-1-AP)

    WB analysis using 32953-1-AP (same clone as 32953-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 32953-1-AP (PANK4 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32953-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

32953-1-PBS bindet in WB, Indirect ELISA PANK4 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen PANK4 fusion protein Ag38232
Vollständiger Name pantothenate kinase 4
Berechnetes Molekulargewicht86 kDa，773aa
Beobachtetes Molekulargewicht86 kDa
GenBank-ZugangsnummerNM_018216.2
Gene symbol PANK4
Gene ID (NCBI) 55229
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

PANK4 (Pantothenate Kinase 4) is a member of the pantothenate kinase family, which is involved in the biosynthesis of coenzyme A (CoA). However, unlike other members of the family, PANK4 lacks the residues required for kinase activity and instead contains a phosphatase domain (DUF89) that can dephosphorylate 4'-phosphopantetheine, an intermediate in CoA biosynthesis (PMID: 30927326). This suggests that PANK4 may act as a pseudoenzyme, regulating cellular CoA levels by antagonizing CoA production (PMID: 39746949).