PAR3 Rekombinanter Antikörper

PAR3 Rekombinant Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IF, ELISA

Konjugation

Unkonjugiert

Publikationen(1)

CloneNo.

241780F7

Kat-Nr. : 84593-1-RR

Synonyme

F2RL2, Proteinase-activated receptor 3, PAR-3, PAR 3, Coagulation factor II receptor-like 2

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  WB analysis using 84593-1-RR

  Various lysates were subjected to SDS PAGE followed by western blot with 84593-1-RR (PAR3 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: MDCK-Zellen, NIH/3T3-Zellen, Rattenhirngewebe, RAW 264.7-Zellen

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:5000-1:50000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• WB: See 1 publications below
• IF: See 1 publications below

Produktinformation

84593-1-RR bindet in WB, IF, ELISA PAR3 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• In Publikationen genannte Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Peptid
• Vollständiger Name: coagulation factor II (thrombin) receptor-like 2
• Berechnetes Molekulargewicht: 374 aa, 43 kDa
• Beobachtetes Molekulargewicht: 45 kDa
• GenBank-Zugangsnummer: BC093648
• Gene symbol: PAR3
• Gene ID (NCBI): 2151
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

PAR3 is a crucial protein involved in the establishment and maintenance of cell polarity across various species. It plays a significant role in organizing cellular structures and functions, particularly in epithelial and neuronal cells. PAR3 has been implicated in various aspects of cancer biology. It can act as a tumor suppressor in epithelial cancers, and its expression or mutations have been associated with the progression and behavior of glioblastoma, pancreatic cancer, and other malignancies.

Publikationen

Species	Application	Title
human,mouse	WB,IF	Stem Cell Res Ther; The PAR6B-PRKCI-PAR3 complex influences alveolar regeneration in patients with the emphysema subtype of chronic obstructive pulmonary disease; Authors - Di Wang