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PARD6B Rekombinanter Antikörper

PARD6B Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

251629D4

Kat-Nr. : 86786-1-PBS

Synonyme

PAR-6 beta, PAR6B, PAR-6B, Partitioning defective 6 homolog beta

Filter:
  • Western Blot (WB) analysis of various lysates using PARD6B Recombinant monoclonal antibody (86786-1-RR)

    WB analysis using 86786-1-RR (same clone as 86786-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86786-1-RR (PARD6B antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86786-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using PARD6B Recombinant monoclonal antibody (86786-1-RR)

    WB analysis using 86786-1-RR (same clone as 86786-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86786-1-RR (PARD6B antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86786-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

86786-1-PBS bindet in WB, Indirect ELISA PARD6B und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen PARD6B fusion protein Ag5083
Vollständiger Name par-6 partitioning defective 6 homolog beta (C. elegans)
Berechnetes Molekulargewicht 41 kDa
Beobachtetes Molekulargewicht52 kDa
GenBank-ZugangsnummerBC060847
Gene symbol PARD6B
Gene ID (NCBI) 84612
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

PARD6B (also named PAR6B) is a member of the PAR6 family. PARD6B is known to play a key role in mammary epithelial cell biology. Several studies have been reported which indicate deregulated PARD6B signaling contributes to malignant epithelial cell phenotypes due predominantly to disrupted polymerization and maintenance of tight junctions (PMID: 22957302). The approximately 4.8-kb long PARD6B mRNA was predominantly detected in both adult and fetal kidneys, while much weaker but significant signals were observed in the placenta, lung, and liver (PMID: 11260256). This antibody detects PARD6B with an apparent molecular weight of 50-53 kDa as has been demonstrated by several researches (PMID: 22496418; 25662318).