PARP14 Rekombinanter Antikörper

PARP14 Rekombinant Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241078C11

Kat-Nr. : 84039-6-PBS

Synonyme

PARP 14, KIAA1268, BAL2, 241078C11

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  WB analysis using 84039-6-RR (same clone as 84039-6-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84039-6-RR (PARP14 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84039-6-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse colon using 84039-6-RR (same clone as 84039-6-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse colon tissue slide using 84039-6-RR (PARP14 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84039-6-PBS in a different storage buffer formulation.

• 

  Affinity and Kinetic Characterization of 84039-6-RR

  Biolayer interferometry (BLl) kinetic assays of 84039-6-RR against Human PARP14 were performed. The affinity constant is 0.685 nM.

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Geprüfte Anwendungen

Produktinformation

84039-6-PBS bindet in WB, IHC, Indirect ELISA PARP14 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: PARP14 fusion protein Ag35007
• Vollständiger Name: poly (ADP-ribose) polymerase family, member 14
• Berechnetes Molekulargewicht: 203kd
• Beobachtetes Molekulargewicht: 200 kDa
• GenBank-Zugangsnummer: NM_017554
• Gene symbol: PARP14
• Gene ID (NCBI): 54625
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

PARP14 (poly (ADP-ribose) polymerase family, member 14) is a PARP family member that has roles in DNA repair, B cell regulation, and focal adhesion (PMID: 25753673). The largest of all the human PARPs is PARP14. PARP14 has been reported to regulate several different pathways involved in immunity, inflammation, and genome stability (PMID: 37703374).