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PARP2 Polyklonaler Antikörper

PARP2 Polyklonal Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 55149-1-PBS

Synonyme

ADPRT2, ADPRTL3, ARTD2, DNA ADP-ribosyltransferase PARP2, EC:2.4.2.-

Filter:
  • Western Blot (WB) analysis of various lysates using PARP2 Polyclonal antibody (55149-1-AP)

    WB analysis using 55149-1-AP (same clone as 55149-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 55149-1-AP (PARP2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55149-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of U2OS cells using PARP2 Polyclonal antibody (55149-1-AP)

    IF Staining of U2OS using 55149-1-AP (same clone as 55149-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed U2OS cells using 55149-1-AP (PARP2 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 55149-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

55149-1-PBS bindet in WB, IF/ICC, Indirect ELISA PARP2 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Peptid
Vollständiger Name poly (ADP-ribose) polymerase 2
Berechnetes Molekulargewicht 66 kDa
Beobachtetes Molekulargewicht 66 kDa
GenBank-ZugangsnummerNM_005484
Gene symbol PARP2
Gene ID (NCBI) 10038
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

PARP2, also named as ADPRT2 and ADPRTL2, is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. This antibody is specific to PARP2 (N-terminal).