PARP9 Polyklonaler Antikörper

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PARP9 Polyklonal Antikörper für WB, IHC, IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Ratte

Anwendung

WB, IHC, IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 17535-1-PBS

Synonyme

ADP-ribosyltransferase diphtheria toxin-like 9, ARTD9, BAL, BAL1, EC:2.4.2.-

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  WB analysis using 17535-1-AP (same clone as 17535-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 17535-1-AP (PARP9 antibody) at dilution of 1:6000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17535-1-PBS in a different storage buffer formulation.

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  IP experiment of MCF-7 using 17535-1-AP (same clone as 17535-1-PBS)

  IP result of anti-PARP9 (IP:17535-1-AP, 4ug; Detection:17535-1-AP 1:3000) with MCF-7 cells lysate 1400 ug. This data was developed using the same antibody clone with 17535-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 17535-1-AP (same clone as 17535-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 17535-1-AP (PARP9 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17535-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 17535-1-AP (same clone as 17535-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 17535-1-AP (PARP9 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17535-1-PBS in a different storage buffer formulation.

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  IHC staining of human kidney using 17535-1-AP (same clone as 17535-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney using 17535-1-AP (PARP9 antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 17535-1-PBS in a different storage buffer formulation.

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  IHC staining of human kidney using 17535-1-AP (same clone as 17535-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney using 17535-1-AP (PARP9 antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 17535-1-PBS in a different storage buffer formulation.

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  IHC staining of human skin using 17535-1-AP (same clone as 17535-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human skin using 17535-1-AP (PARP9 antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 17535-1-PBS in a different storage buffer formulation.

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  IHC staining of human skin using 17535-1-AP (same clone as 17535-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human skin using 17535-1-AP (PARP9 antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 17535-1-PBS in a different storage buffer formulation.

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  IHC staining of human lung using 17535-1-AP (same clone as 17535-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung using 17535-1-AP (PARP9 antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 17535-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human lung using 17535-1-AP (same clone as 17535-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung using 17535-1-AP (PARP9 antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 17535-1-PBS in a different storage buffer formulation.

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  IHC staining of human ovary using 17535-1-AP (same clone as 17535-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary using 17535-1-AP (PARP9 antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 17535-1-PBS in a different storage buffer formulation.

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  IHC staining of human ovary using 17535-1-AP (same clone as 17535-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary using 17535-1-AP (PARP9 antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 17535-1-PBS in a different storage buffer formulation.

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  IHC staining of human lymphoma using 17535-1-AP (same clone as 17535-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lymphoma using 17535-1-AP (PARP9 antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 17535-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human lymphoma using 17535-1-AP (same clone as 17535-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lymphoma using 17535-1-AP (PARP9 antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 17535-1-PBS in a different storage buffer formulation.

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  IHC staining of human heart using 17535-1-AP (same clone as 17535-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human heart using 17535-1-AP (PARP9 antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 17535-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human heart using 17535-1-AP (same clone as 17535-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human heart using 17535-1-AP (PARP9 antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 17535-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

17535-1-PBS bindet in WB, IHC, IP, Indirect ELISA PARP9 und zeigt Reaktivität mit human, Ratten

• Getestete Reaktivität: human, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: PARP9 fusion protein Ag11587
• Vollständiger Name: poly (ADP-ribose) polymerase family, member 9
• Berechnetes Molekulargewicht: 819 aa, 92 kDa
• Beobachtetes Molekulargewicht: 88 kDa
• GenBank-Zugangsnummer: BC039580
• Gene symbol: PARP9
• Gene ID (NCBI): 83666
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Poly(ADP-ribosyl)ation is a post-translational modification of proteins mediated by one of the 17 members of the poly(ADP-ribose) polymerases (PARP). PARP-9 belongs to the subfamily of macroPARPs, associating one to three macro domains to the PARP domain. Overexpression of PARP-9 stimulates cell migration in vitro, suggesting a role for PARP-9 in the promotion of malignant B cell migration and dissemination in high risk DLBCL. PARP-9 is also likely a transcription coactivator, its overexpression in B lymphocytes, stimulated by IFNγ, inducing the transcription of IFNγ-controlled genes.