PAX8 Rekombinanter Antikörper

PAX8 Rekombinant Antikörper für WB, IHC, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IHC, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

6B14

Kat-Nr. : 80756-1-PBS

Synonyme

PAX-8, PAX 8, Paired box protein Pax-8, Paired box protein Pax 8, paired box 8



Geprüfte Anwendungen

Produktinformation

80756-1-PBS bindet in WB, IHC, IF/ICC, Indirect ELISA PAX8 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen PAX8 fusion protein Ag0306
Vollständiger Name paired box 8
Berechnetes Molekulargewicht 48 kDa
Beobachtetes Molekulargewicht48 kDa, 58 kDa
GenBank-ZugangsnummerBC001060
Gene symbol PAX8
Gene ID (NCBI) 7849
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

PAX8 is a member of the paired box (PAX) family of transcription factors, typically containing a paired box domain and a paired-type homeodomain. It is expressed during organogenesis of the thyroid gland, kidney and Mullerian system. It is thought to regulate the expression of Wilms tumor suppressor (WT1) gene and mutations in PAX8 have been associated with Wilms tumor cells, thyroid and ovarian carcinomas. PAX8 is a useful marker in distinguishing ovarian carcinomas from mammary carcinomas (PMID: 18724243). PAX8 is expressed in a high percentage of ovarian serous, endometrioid, and clear cell carcinomas, but only rarely in primary ovarian mucinous adenocarcinoma.