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PBX3 Rekombinanter Antikörper

PBX3 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

251518A4

Kat-Nr. : 86595-3-PBS

Synonyme

Homeobox protein PBX3, pre B cell leukemia homeobox 3, Pre-B-cell leukemia transcription factor 3

Filter:
  • Western Blot (WB) analysis of various lysates using PBX3 Recombinant monoclonal antibody (86595-3-RR)

    WB analysis using 86595-3-RR (same clone as 86595-3-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86595-3-RR (PBX3 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86595-3-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

86595-3-PBS bindet in WB, Indirect ELISA PBX3 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen PBX3 fusion protein Ag3239
Vollständiger Name pre-B-cell leukemia homeobox 3
Berechnetes Molekulargewicht 434 aa, 47 kDa
Beobachtetes Molekulargewicht 47-50 kDa
GenBank-ZugangsnummerBC016977
Gene symbol PBX3
Gene ID (NCBI) 5090
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

PBX3 is a homeodomain-containing transcription factor of the pre-B cell leukemia (PBX) family, members of which have extensive roles in early development and some adult processes. It plays crucial roles in embryonic development, organogenesis, and cell differentiation by regulating the expression of downstream target genes. Beyond its physiological functions, PBX3 is increasingly recognized for its significant involvement in oncogenesis. It is frequently overexpressed in various malignancies, including leukemias and solid tumors, where it promotes cell proliferation, inhibits apoptosis, enhances invasion and metastasis, and contributes to chemotherapy resistance.