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PCDH21 Polyklonaler Antikörper

PCDH21 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 17424-1-PBS

Synonyme

Protocadherin-21, PRCAD, Photoreceptor cadherin, KIAA1775, CDHR1

Filter:
  • Western Blot (WB) analysis of various lysates using PCDH21 Polyclonal antibody (17424-1-AP)

    WB analysis using 17424-1-AP (same clone as 17424-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 17424-1-AP (PCDH21 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17424-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

17424-1-PBS bindet in WB, Indirect ELISA PCDH21 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen PCDH21 fusion protein Ag11451
Vollständiger Name protocadherin 21
Berechnetes Molekulargewicht 745 aa, 82 kDa
Beobachtetes Molekulargewicht110-120 kDa
GenBank-ZugangsnummerBC038799
Gene symbol PCDH21
Gene ID (NCBI) 92211
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Protocadherins, which constitute the largest subgroup within the cadherin superfamily, are predominantly expressed in the nervous system and are probably involved in the regulation of neuronal recognition and connectivity (PMID: 17936607; 12231349; 17133224). PCDH21 (protocadherin 21), also known as CDHR1, is a photoreceptor-specific cadherin protein containing six ECs and an intracellular domain. The mutations of PCDH21 cause recessive retinal degeneration and autosomal recessive cone-rod dystrophy in humans (PMID: 16288196; PMID: 20805371). The full length of the PCDH21 protein is 120 kDa, the N-terminal soluble fragment is 95 kDa, and the C-terminal fragment is 25 kDa (PMID: 35066146; PMID: 18654668; PMID: 33964272).