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PCDH21 Rekombinanter Antikörper

PCDH21 Rekombinant Antikörper für WB, Cytometric bead array, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Cytometric bead array, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241134E10

Kat-Nr. : 84084-3-PBS

Synonyme

241134E10, Cadherin-related family member 1, CDHR1, KIAA1775, Photoreceptor cadherin

Filter:
  • Western Blot (WB) analysis of Y79 cells using PCDH21 Recombinant antibody (84084-3-RR)

    WB analysis of Y79 using 84084-3-RR (same clone as 84084-3-PBS)

    Y79 cells were subjected to SDS PAGE followed by western blot with 84084-3-RR (PCDH21 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84084-3-PBS in a different storage buffer formulation.

  • Cytometric bead array standard curve of MP00999-2

    Cytometric bead array standard curve of MP00999-2

    Cytometric bead array standard curve of MP00999-2, PCDH21 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 84084-3-PBS. Detection antibody: 84084-2-PBS. Standard: Ag11451. Range: 0.313-40 ng/mL.

  • Affinity and Kinetic Characterization of 84084-3-RR

    Affinity and Kinetic Characterization of 84084-3-RR

    Biolayer interferometry (BLl) kinetic assays of 84084-3-RR against Human PCDH21 were performed. The affinity constant is 0.196 nM.

Geprüfte Anwendungen

Produktinformation

84084-3-PBS bindet in WB, Cytometric bead array, Indirect ELISA PCDH21 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen PCDH21 fusion protein Ag11451
Vollständiger Name protocadherin 21
Berechnetes Molekulargewicht 745 aa, 82 kDa
Beobachtetes Molekulargewicht120 kDa
GenBank-ZugangsnummerBC038799
Gene symbol PCDH21
Gene ID (NCBI) 92211
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Protocadherins, which constitute the largest subgroup within the cadherin superfamily, are predominantly expressed in the nervous system and are probably involved in the regulation of neuronal recognition and connectivity (PMID: 17936607; 12231349; 17133224). PCDH21 (protocadherin 21), also known as CDHR1, is a photoreceptor-specific cadherin protein containing six ECs and an intracellular domain. The mutations of PCDH21 cause recessive retinal degeneration and autosomal recessive cone-rod dystrophy in humans (PMID: 16288196; PMID: 20805371). The full length of the PCDH21 protein is 120 kDa, the N-terminal soluble fragment is 95 kDa, and the C-terminal fragment is 25 kDa (PMID: 35066146; PMID: 18654668; PMID: 33964272).