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PCDHB1 Polyklonaler Antikörper

PCDHB1 Polyklonal Antikörper für IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 31966-1-PBS

Synonyme

Protocadherin beta-1, Protocadherin Beta 1 , PCDH-beta-1

Filter:
  • Immunoprecipitation (IP) experiment of mouse skeletal muscle tissue using PCDHB1 Polyclonal antibody (31966-1-AP)

    IP experiment of mouse skeletal muscle using 31966-1-AP (same clone as 31966-1-PBS)

    IP result of anti-PCDHB1 (IP:31966-1-AP, 4ug; Detection:31966-1-AP 1:500) with mouse skeletal muscle tissue lysate 1040 ug. This data was developed using the same antibody clone with 31966-1-PBS in a different storage buffer formulation.

  • Immunoprecipitation (IP) experiment of rat skeletal muscle tissue using PCDHB1 Polyclonal antibody (31966-1-AP)

    IP experiment of rat skeletal muscle using 31966-1-AP (same clone as 31966-1-PBS)

    IP result of anti-PCDHB1 (IP:31966-1-AP, 4ug; Detection:31966-1-AP 1:500) with rat skeletal muscle tissue lysate 1800 ug. This data was developed using the same antibody clone with 31966-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

31966-1-PBS bindet in IP, Indirect ELISA PCDHB1 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen PCDHB1 fusion protein Ag35435
Vollständiger Name protocadherin beta 1
Beobachtetes Molekulargewicht80 kDa
GenBank-ZugangsnummerBC112096
Gene symbol PCDHB1
Gene ID (NCBI) 29930
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

PCDHB1 (Protocadherin Beta 1) is a member of the protocadherin beta gene cluster, which belongs to the Cadherin superfamily and is expressed primarily in the nervous system. It encodes a cell adhesion protein containing six extracellular adhesion protein structural domains and a distinct cytoplasmic tail involved in the establishment and function of intercellular junctions. PCDHB1 plays an important role in neurodevelopment, and its aberrant expression has been associated with a variety of neurodevelopmental disorders, for example, PCDHB1 expression is upregulated in the brains of patients with Rett syndrome, which may be related to the neuropathological features of the disease. In addition, members of the PCDHB1 gene cluster are involved in neuronal self-recognition, avoidance, and connection establishment with other neurons.