PCDHB10 Polyklonaler Antikörper

PCDHB10 Polyklonal Antikörper für IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 14785-1-PBS

Synonyme

---

• 

  IHC staining of human pancreas cancer using 14785-1-AP (same clone as 14785-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 14785-1-AP (PCDHB10 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14785-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human pancreas cancer using 14785-1-AP (same clone as 14785-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 14785-1-AP (PCDHB10 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14785-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human gliomas using 14785-1-AP (same clone as 14785-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human gliomas tissue slide using 14785-1-AP (PCDHB10 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14785-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human gliomas using 14785-1-AP (same clone as 14785-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human gliomas tissue slide using 14785-1-AP (PCDHB10 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14785-1-PBS in a different storage buffer formulation.

---

Geprüfte Anwendungen

Produktinformation

14785-1-PBS bindet in IHC, Indirect ELISA PCDHB10 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: PCDHB10 fusion protein Ag6427
• Vollständiger Name: protocadherin beta 10
• Berechnetes Molekulargewicht: 88 kDa
• GenBank-Zugangsnummer: BC031837
• Gene symbol: PCDHB10
• Gene ID (NCBI): 56126
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Protocadherins, which constitute the largest subgroup within the cadherin superfamily, are predominantly expressed in the nervous system and are probably involved in the regulation of neuronal recognition and connectivity (PMID: 17936607; 12231349; 17133224). The protocadherin subfamily can be further subdivided into three groups: the clustered protocadherins, comprising α-, β- and γ-protocadherins; δ-protocadherins; and others, many of which are solitary (PMID: 17133224). PCDHB10 belongs to the β-protocadherin (PCDHB) cluster. PCDHB cluster acts as a DNA methylation marker of aggressiveness in neuroblastoma (PMID: 26103900).