PCDHGC5 Polyklonaler Antikörper

PCDHGC5 Polyklonal Antikörper für IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 23848-1-PBS

Synonyme

Protocadherin gamma-C5, PCDHGC, PCDH-gamma-C5

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  IHC staining of human lung cancer using 23848-1-AP (same clone as 23848-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 23848-1-AP (PCDHGC5 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 23848-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human lung cancer using 23848-1-AP (same clone as 23848-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 23848-1-AP (PCDHGC5 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 23848-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

23848-1-PBS bindet in IHC, Indirect ELISA PCDHGC5 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: PCDHGC5 fusion protein Ag20867
• Vollständiger Name: protocadherin gamma subfamily C, 5
• Berechnetes Molekulargewicht: 581aa,65 kDa; 944aa,102 kDa
• GenBank-Zugangsnummer: BC112081
• Gene symbol: PCDHGC5
• Gene ID (NCBI): 56097
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-affinitätsgereinigt
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Protocadherins, which constitute the largest subgroup within the cadherin superfamily, are predominantly expressed in the nervous system and are probably involved in the regulation of neuronal recognition and connectivity (PMID: 17936607; 12231349; 17133224). The protocadherin subfamily can be further subdivided into three groups: the clustered protocadherins, comprising α-, β- and γ-protocadherins; δ-protocadherins; and others, many of which are solitary (PMID: 17133224). Disruption of the γ-protocadherins locus causes neonatal lethality, and Pcdhgc3, Pcdhgc4, and Pcdhgc5 are essential for the observed lethality.