PD-ECGF Monoklonaler Antikörper

PD-ECGF Monoklonal Antikörper für Cytometric bead array, Indirect ELISA

Wirt / Isotyp

Maus / IgG2a

Getestete Reaktivität

human

Anwendung

Cytometric bead array, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

1B3E7

Kat-Nr. : 67104-2-PBS

Synonyme

TYMP, EC:2.4.2.4, ECGF1, Gliostatin, Platelet-derived endothelial cell growth factor



Geprüfte Anwendungen

Produktinformation

67104-2-PBS bindet in Cytometric bead array, Indirect ELISA PD-ECGF und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgG2a
Klonalität Monoklonal
Typ Antikörper
Immunogen PD-ECGF fusion protein Ag28631
Vollständiger Name thymidine phosphorylase
Berechnetes Molekulargewicht 482 aa, 50 kDa
GenBank-ZugangsnummerBC018160
Gene symbol Thymidine phosphorylase
Gene ID (NCBI) 1890
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Platelet derived endothelial cell growth factor (PD-ECGF), also known as thymidine phosphorylase (TP), induces migration and angiogenesis in endothelial and tumor cells, and was upregulated in various malignancies compared to that in normal tissues. Interestingly, PD-ECGF has dual effect on tumor development and chemotherapy. It could stimulate cancer cell migration and proliferation. On the other hand, some chemotherapeutic agents (5-fluorouracil, capecitabine, etc.] were converted to their active forms through TP enzymes.