PD-ECGF Monoklonaler Antikörper
PD-ECGF Monoklonal Antikörper für Cytometric bead array, Indirect ELISA
Wirt / Isotyp
Maus / IgG2a
Getestete Reaktivität
human
Anwendung
Cytometric bead array, Indirect ELISA
Konjugation
Unkonjugiert
CloneNo.
1B3E7
Kat-Nr. : 67104-2-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
67104-2-PBS bindet in Cytometric bead array, Indirect ELISA PD-ECGF und zeigt Reaktivität mit human
| Getestete Reaktivität | human |
| Wirt / Isotyp | Maus / IgG2a |
| Klonalität | Monoklonal |
| Typ | Antikörper |
| Immunogen | PD-ECGF fusion protein Ag28631 |
| Vollständiger Name | thymidine phosphorylase |
| Berechnetes Molekulargewicht | 482 aa, 50 kDa |
| GenBank-Zugangsnummer | BC018160 |
| Gene symbol | Thymidine phosphorylase |
| Gene ID (NCBI) | 1890 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Protein-A-Reinigung |
| Lagerungspuffer | PBS only |
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
Platelet derived endothelial cell growth factor (PD-ECGF), also known as thymidine phosphorylase (TP), induces migration and angiogenesis in endothelial and tumor cells, and was upregulated in various malignancies compared to that in normal tissues. Interestingly, PD-ECGF has dual effect on tumor development and chemotherapy. It could stimulate cancer cell migration and proliferation. On the other hand, some chemotherapeutic agents (5-fluorouracil, capecitabine, etc.] were converted to their active forms through TP enzymes.

