• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

PD-ECGF Rekombinanter Antikörper

PD-ECGF Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

251581B2

Kat-Nr. : 86618-3-PBS

Synonyme

TYMP, EC:2.4.2.4, ECGF1, Gliostatin, Platelet-derived endothelial cell growth factor

Filter:
  • Western Blot (WB) analysis of various lysates using PD-ECGF Recombinant monoclonal antibody (86618-3-RR)

    WB analysis using 86618-3-RR (same clone as 86618-3-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86618-3-RR (PD-ECGF antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86618-3-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using PD-ECGF Recombinant monoclonal antibody (86618-3-RR)

    WB analysis using 86618-3-RR (same clone as 86618-3-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86618-3-RR (PD-ECGF antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86618-3-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 86618-3-RR

    Affinity and Kinetic Characterization of 86618-3-RR

    Biolayer interferometry (BLl) kinetic assays of 86618-3-RR against Human PD-ECGF were performed. The affinity constant is 1.64 nM.

Geprüfte Anwendungen

Produktinformation

86618-3-PBS bindet in WB, Indirect ELISA PD-ECGF und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen PD-ECGF fusion protein Ag3052
Vollständiger Name thymidine phosphorylase
Berechnetes Molekulargewicht 482 aa, 50 kDa
Beobachtetes Molekulargewicht 50 kDa
GenBank-ZugangsnummerBC018160
Gene symbol Thymidine phosphorylase
Gene ID (NCBI) 1890
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Platelet derived endothelial cell growth factor (PD-ECGF), also known as thymidine phosphorylase (TP), induces migration and angiogenesis in endothelial and tumor cells, and was upregulated in various malignancies compared to that in normal tissues. Interestingly, PD-ECGF has dual effect on tumor development and chemotherapy. It could stimulate cancer cell migration and proliferation. On the other hand, some chemotherapeutic agents (5-fluorouracil, capecitabine, etc.) were converted to their active forms through TP enzymes.