PD-L2/CD273 Rekombinanter Antikörper

PD-L2/CD273 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

241728D8

Kat-Nr. : 98241-1-RR

Synonyme

CD273, Butyrophilin B7-DC, Btdc, B7-DC, B7dc

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  FC experiment of mouse splenocytes using 98241-1-RR

  1x10^6 untreated or GM-CSF treated mouse splenocytes were surface stained with 0.25 ug Anti-Mouse PD-L2/CD273 Rabbit Recombinant Antibody (98241-1-RR, Clone: 241728D8) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with APC Anti-Mouse CD11c (N418) (APC-65130, Clone: N418). Cells were not fixed.

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  FC experiment of mouse splenocytes using 98241-1-RR

  1x10^6 GM-CSF treated mouse splenocytes were surface stained with 0.25 ug Anti-Mouse PD-L2/CD273 Rabbit Recombinant Antibody (98241-1-RR, Clone:241728D8) (red) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). 1x10^6 untreated mouse splenocytes were surface stained with 0.25 ug Anti-Mouse PD-L2/CD273 Rabbit Recombinant Antibody (98241-1-RR, Clone:241728D8) (black, dashed) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: GM-CSF treated mouse splenocytes

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

98241-1-RR bindet in FC PD-L2/CD273 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Rekombinantes Protein
• Vollständiger Name: programmed cell death 1 ligand 2
• Berechnetes Molekulargewicht: 28kDa
• GenBank-Zugangsnummer: NM_021396.2
• Gene symbol: Pdcd1lg2
• Gene ID (NCBI): 58205
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS with 0.09% sodium azide
• Lagerungsbedingungen: Store at 2 - 8°C. Stable for one year after shipment.

Hintergrundinformationen

Programmed cell death ligand 2 (PD-L2, also known as CD273, or B7-DC), is one of the B7 family molecules which are type I transmembrane proteins belonging to the immunoglobulin superfamily. PD-L2 was identified both by its homology to PD-L1 and by analysis of genes differentially expressed in libraries generated from dendritic cells (DC) and activated macrophages (PMID: 14515254). PD-L2 is a second ligand for PD-1, a costimulatory molecule that plays an inhibitory role in regulating T cell activation in the periphery.