PD-L2/CD273 Rekombinanter Antikörper

PD-L2/CD273 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

FITC Plus Fluorescent Dye

CloneNo.

241728D8

Kat-Nr. : FITC-98241

Synonyme

PD-L2/B7-DC, 241728D8, B7dc, B7-DC, Btdc

---

• 

  FC experiment of mouse splenocytes using FITC-98241

  1x10^6 untreated or GM-CSF treated mouse splenocytes were surface stained with APC Anti-Mouse CD11c and 0.25 ug FITC Plus Anti-Mouse PD-L2/CD273 Rabbit RecAb (FITC-98241, Clone: 241728D8). Cells were not fixed.

• 

  FC experiment of mouse splenocytes using FITC-98241

  1x10^6 GM-CSF treated mouse splenocytes were surface stained with 0.25 ug FITC Plus Anti-Mouse PD-L2/CD273 Rabbit RecAb (FITC-98241, Clone: 241728D8) (red) or FITC Plus Rabbit IgG Isotype Control RecAb (FITC-98136, Clone: 240953C9) (blue). 1x10^6 untreated mouse splenocytes were surface stained with 0.25 ug FITC Plus Anti-Mouse PD-L2/CD273 Rabbit RecAb (FITC-98241, Clone: 241728D8) (black, dashed). Cells were not fixed.

---

Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: GM-CSF treated mouse splenocytes

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

FITC-98241 bindet in FC PD-L2/CD273 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: PD-L2/CD273 fusion protein Eg1842
• Vollständiger Name: programmed cell death 1 ligand 2
• Berechnetes Molekulargewicht: 28kDa
• GenBank-Zugangsnummer: NM_021396.2
• Gene symbol: Pdcd1lg2
• Gene ID (NCBI): 58205
• Konjugation: FITC Plus Fluorescent Dye
• Excitation/Emission maxima wavelengths: 495 nm / 524 nm
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.09% sodium azide
• Lagerungsbedingungen: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Hintergrundinformationen

Programmed cell death ligand 2 (PD-L2, also known as CD273, or B7-DC), is one of the B7 family molecules which are type I transmembrane proteins belonging to the immunoglobulin superfamily. PD-L2 was identified both by its homology to PD-L1 and by analysis of genes differentially expressed in libraries generated from dendritic cells (DC) and activated macrophages (PMID: 14515254). PD-L2 is a second ligand for PD-1, a costimulatory molecule that plays an inhibitory role in regulating T cell activation in the periphery.