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PDCD6/ALG2 Rekombinanter Antikörper

PDCD6/ALG2 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

250087B4

Kat-Nr. : 85792-5-PBS

Synonyme

ALG2, PDCD6, ALG 2, ALG-2, Apoptosis-linked gene 2 protein homolog

Filter:
  • Western Blot (WB) analysis of various lysates using PDCD6/ALG2 Recombinant antibody (85792-5-RR)

    WB analysis using 85792-5-RR (same clone as 85792-5-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85792-5-RR (PDCD6/ALG2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85792-5-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of HeLa cells using PDCD6/ALG2 Recombinant antibody (85792-5-RR)

    WB analysis of HeLa using 85792-5-RR (same clone as 85792-5-PBS)

    HeLa cells were subjected to SDS PAGE followed by western blot with 85792-5-RR (PDCD6/ALG2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85792-5-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 85792-5-RR

    Affinity and Kinetic Characterization of 85792-5-RR

    Biolayer interferometry (BLl) kinetic assays of 85792-5-RR against Human PDCD6/ALG2 were performed. The affinity constant is 5.93 nM.

Geprüfte Anwendungen

Produktinformation

85792-5-PBS bindet in WB, Indirect ELISA PDCD6/ALG2 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen PDCD6/ALG2 fusion protein Ag2949
Vollständiger Name programmed cell death 6
Berechnetes Molekulargewicht 191 aa, 22 kDa
Beobachtetes Molekulargewicht 15-22 kDa
GenBank-ZugangsnummerBC012384
Gene symbol PDCD6
Gene ID (NCBI) 10016
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Programmed cell death protein 6 (PDCD6) is also named as ALG2. PDCD6 is an evolutionarily conserved Ca2+-binding protein. PDCD6 is required for coat protein complex II-dependent endoplasmic reticulum-to-Golgi apparatus vesicular transport in the cytoplasm (PMID: 39934130). PDCD6 is involved in regulating multifaceted and pleiotropic cellular processes in different cellular compartments. The nuclear PDCD6 regulates apoptosis and alternative splicing. And cytoplasmic PDCD6 is involved in the regulation of cytoskeletal dynamics and innate immune responses. Additionally, membranous PDCD6 participates in membrane repair through endosomal sorting complex required for transport complex-dependent membrane budding. (PMID: 38436472). PDCD6 also acts as a regulator of cytosolic DNA-induced immune responses by modulating STING transport (PMID: 34787301).