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PDE1C Polyklonaler Antikörper

PDE1C Polyklonal Antikörper für WB, IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 13785-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of human heart tissue using PDE1C Polyclonal antibody (13785-1-AP)

    WB analysis of human heart using 13785-1-AP (same clone as 13785-1-PBS)

    human heart tissue were subjected to SDS PAGE followed by western blot with 13785-1-AP (PDE1C antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13785-1-PBS in a different storage buffer formulation.

  • Immunoprecipitation (IP) experiment of mouse heart tissue using PDE1C Polyclonal antibody (13785-1-AP)

    IP experiment of mouse heart using 13785-1-AP (same clone as 13785-1-PBS)

    IP result of anti-PDE1C (IP:13785-1-AP, 4ug; Detection:13785-1-AP 1:500) with mouse heart tissue lysate 4000ug. This data was developed using the same antibody clone with 13785-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

13785-1-PBS bindet in WB, IP, Indirect ELISA PDE1C und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen PDE1C fusion protein Ag4798
Vollständiger Name phosphodiesterase 1C, calmodulin-dependent 70kDa
Berechnetes Molekulargewicht 634 aa, 72 kDa
Beobachtetes Molekulargewicht 68 kDa
GenBank-ZugangsnummerBC022525
Gene symbol PDE1C
Gene ID (NCBI) 5137
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. PDE1C, is calmodulin-dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex. Expression of PDE1C may be an important component in signal transduction pathways mediated by calcium that permit cell cycle traverse and proliferation(PMID:9366577). It has 2 isoforms produced by alternative splicing.