PDGFR alpha/CD140a Rekombinanter Antikörper

PDGFR alpha/CD140a Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

242025B3

Kat-Nr. : 98256-1-PBS

Synonyme

EC:2.7.10.1, CD140a, CD140 antigen-like family member A, Alpha-type platelet-derived growth factor receptor, Alpha platelet-derived growth factor receptor

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  FC experiment of NIH/3T3 using 98256-1-RR (same clone as 98256-1-PBS)

  1x10^6 NIH/3T3 cells were surface stained with 0.25 ug Anti-Mouse PDGFR alpha/CD140a Rabbit Recombinant Antibody (98256-1-RR, Clone: 242025B3) and PE-Conjugated Goat Anti-Rabbit IgG(H+L) (red), or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) and PE-Conjugated Goat Anti-Rabbit IgG(H+L) (blue). Cells were not fixed. This data was developed using the same antibody clone with 98256-1-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 98256-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98256-1-RR against Mouse PDGFR alpha/CD140a were performed. The affinity constant is below 1 pM.

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Geprüfte Anwendungen

Produktinformation

98256-1-PBS bindet in FC PDGFR alpha/CD140a und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Rekombinantes Protein
• Vollständiger Name: platelet derived growth factor receptor, alpha polypeptide
• Berechnetes Molekulargewicht: 123kDa
• GenBank-Zugangsnummer: NM_001083316.2
• Gene symbol: Pdgfra
• Gene ID (NCBI): 18595
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C.

Hintergrundinformationen

Platelet-derived growth factor receptor alpha (PDGFR alpha, also known as CD140a) is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. PDGFRA is implicated in the regulation of embryonic development, tumorigenesis, cell proliferation, survival, and chemotaxis. Mutations in the PDGFRA gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.