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PDGFR alpha/CD140a Rekombinanter Antikörper

PDGFR alpha/CD140a Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241658G6

Kat-Nr. : 84383-2-PBS

Synonyme

PDGFRA, 241658G6, Alpha platelet-derived growth factor receptor, Alpha-type platelet-derived growth factor receptor, CD140 antigen-like family member A

Filter:
  • Western Blot (WB) analysis of various lysates using PDGFR alpha/CD140a Recombinant antibody (84383-2-RR)

    WB analysis using 84383-2-RR (same clone as 84383-2-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84383-2-RR (PDGFRA antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84383-2-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84383-2-RR

    Affinity and Kinetic Characterization of 84383-2-RR

    Biolayer interferometry (BLl) kinetic assays of 84383-2-RR against Human PDGFR alpha/CD140a were performed. The affinity constant is 1.21 nM.

Geprüfte Anwendungen

Produktinformation

84383-2-PBS bindet in WB, Indirect ELISA PDGFR alpha/CD140a und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Rekombinantes Protein
Vollständiger Name platelet-derived growth factor receptor, alpha polypeptide
Berechnetes Molekulargewicht 123 kDa
Beobachtetes Molekulargewicht170-190 kDa
GenBank-ZugangsnummerBC015186
Gene symbol PDGFR alpha
Gene ID (NCBI) 5156
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Platelet-derived growth factor receptor alpha (PDGFRA, also known as CD140a) is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. PDGFRA is implicated in the regulation of embryonic development, tumorigenesis, cell proliferation, survival, and chemotaxis. Mutations in the PDGFRA gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.