PDIR Polyklonaler Antikörper

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• KD/KO Validated

PDIR Polyklonal Antikörper für WB, IHC, IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 29593-1-PBS

Synonyme

PDIA5, EC:5.3.4.1, Protein disulfide isomerase A5, Protein disulfide isomerase-related protein, Protein disulfide-isomerase A5

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  WB analysis using 29593-1-AP (same clone as 29593-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 29593-1-AP (PDIR antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29593-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 29593-1-AP (same clone as 29593-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 29593-1-AP (PDIR antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29593-1-PBS in a different storage buffer formulation.

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  IP experiment of mouse liver using 29593-1-AP (same clone as 29593-1-PBS)

  IP result of anti-PDIR (IP:29593-1-AP, 4ug; Detection:29593-1-AP 1:5000) with mouse liver tissue lysate 2400 ug. This data was developed using the same antibody clone with 29593-1-PBS in a different storage buffer formulation.

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  IHC staining of human placenta using 29593-1-AP (same clone as 29593-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 29593-1-AP (PDIR antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29593-1-PBS in a different storage buffer formulation.

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  IHC staining of human placenta using 29593-1-AP (same clone as 29593-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 29593-1-AP (PDIR antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29593-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

29593-1-PBS bindet in WB, IHC, IP, Indirect ELISA PDIR und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: PDIR fusion protein Ag31479
• Vollständiger Name: protein disulfide isomerase family A, member 5
• Berechnetes Molekulargewicht: 60 kDa
• Beobachtetes Molekulargewicht: 60 kDa
• GenBank-Zugangsnummer: BC001625
• Gene symbol: PDIR
• Gene ID (NCBI): 10954
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

PDIR(Protein disulfide isomerase-related protein), also known as PDIA5 (Protein Disulfide Isomerase Family A Member 5), is a member of the PDI gene family and also exhibits chaperone-like activity. PDIR protein is correlated with immune infiltration, which is highly expressed in glioma and participates in glioma progression(PMID: 33664747). PDIR contributes to disulfide bond rearrangement in ATF6α under stress conditions that necessary for ATF6α activation upon ER stress(PMID: 24636989).