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PDLIM5 Monoklonaler Antikörper

PDLIM5 Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgM

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

1H9C9

Kat-Nr. : 67651-1-PBS

Synonyme

ENH, ENH1, Enigma homolog, L9, LIM, PDLIM5, PDZ and LIM domain 5, PDZ and LIM domain protein 5

Filter:
  • Western Blot (WB) analysis of various lysates using PDLIM5 Monoclonal antibody (67651-1-Ig)

    WB analysis using 67651-1-Ig (same clone as 67651-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67651-1-Ig (PDLIM5 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67651-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

67651-1-PBS bindet in WB, Indirect ELISA PDLIM5 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgM
Klonalität Monoklonal
Typ Antikörper
Immunogen PDLIM5 fusion protein Ag25059
Vollständiger Name PDZ and LIM domain 5
Berechnetes Molekulargewicht 64 kDa
Beobachtetes Molekulargewicht 63-69 kDa
GenBank-ZugangsnummerBC008741
Gene symbol PDLIM5
Gene ID (NCBI) 10611
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Euglobulin-Präzipitation
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

PDLIM5 (PDZ and LIM domain 5), formerly known as enigma homolog (ENH), is a cytoplasmic protein containing PDZ domain and LIM domain at N terminus and C terminus, respectively. PDLIM5 gene generates several splicing variants, EZH1 to EZH4. The long isoform, ENH1, is widely expressed in various tissues including heart, brain, spleen, liver and kidney. In comparison, shorter isoforms that lack the LIM motifs are expressed in cardiac (ENH3) and skeletal muscle (ENH2, ENH3, and ENH4). ENH1 is essential for differentiation of striated muscles through interaction with other proteins. In addition, PDLIM5 is also involved in mood disorders, such as schizophrenia, bipolar disorder, and major depression.