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PEA15 Rekombinanter Antikörper

PEA15 Rekombinant Antikörper für IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241044H6

Kat-Nr. : 83958-3-PBS

Synonyme

MAT1H, MAT1, HUMMAT1H, HMAT1, Astrocytic phosphoprotein PEA-15

Filter:
  • Immunofluorescence (IF) / fluorescent staining of A431 cells using PEA15 Recombinant antibody (83958-3-RR)

    IF Staining of A431 using 83958-3-RR (same clone as 83958-3-PBS)

    Immunofluorescent analysis of (4% PFA) fixed A431 cells using PEA15 antibody (83958-3-RR, Clone: 241044H6 ) at dilution of 1:250 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 83958-3-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of A431 cells using PEA15 Recombinant antibody (83958-3-RR)

    IF Staining of A431 using 83958-3-RR (same clone as 83958-3-PBS)

    Immunofluorescent analysis of (4% PFA) fixed A431 cells using PEA15 antibody (83958-3-RR, Clone: 241044H6 ) at dilution of 1:500 and CoraLite®594-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-4). This data was developed using the same antibody clone with 83958-3-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 83958-3-RR

    Affinity and Kinetic Characterization of 83958-3-RR

    Biolayer interferometry (BLl) kinetic assays of 83958-3-RR against Human PEA15 were performed. The affinity constant is 6.95 nM.

Geprüfte Anwendungen

Produktinformation

83958-3-PBS bindet in IF/ICC, Indirect ELISA PEA15 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen PEA15 fusion protein Ag13782
Vollständiger Name phosphoprotein enriched in astrocytes 15
Berechnetes Molekulargewicht 130 aa, 15 kDa
Beobachtetes Molekulargewicht 15 kDa
GenBank-ZugangsnummerBC002426
Gene symbol PEA15
Gene ID (NCBI) 8682
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Phosphoprotein Enriched in Astrocytes 15 kDa (PEA15), also known as PED-15, is a small, death effector-domain (DED)-containing protein that was recently demonstrated to inhibit tumor necrosis factor-α-induced apoptosis and to reverse the inhibition of integrin activation due to H-Ras. PEA15 is a 15 kDa protein that is highly expressed in the nervous system with particularly high levels in astrocytes and neurons of the hippocampus. PEA15 is a cytoplasmic protein that sits at an important junction in intracellular signalling and can regulate diverse cellular processes, such as proliferation and apoptosis, dependent upon stimulation.