Serpin F1/PEDF Monoklonaler Antikörper
Serpin F1/PEDF Monoklonal Antikörper für WB, Indirect ELISA
Wirt / Isotyp
Maus / IgG1
Getestete Reaktivität
Hausschwein, human
Anwendung
WB, Indirect ELISA
Konjugation
Unkonjugiert
CloneNo.
2C5C8
Kat-Nr. : 66554-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
66554-1-PBS bindet in WB, Indirect ELISA Serpin F1/PEDF und zeigt Reaktivität mit Hausschwein, human
| Getestete Reaktivität | Hausschwein, human |
| Wirt / Isotyp | Maus / IgG1 |
| Klonalität | Monoklonal |
| Typ | Antikörper |
| Immunogen | Serpin F1/PEDF fusion protein Ag26660 |
| Vollständiger Name | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| Berechnetes Molekulargewicht | 418 aa, 46 kDa |
| Beobachtetes Molekulargewicht | 46-50 kDa |
| GenBank-Zugangsnummer | BC013984 |
| Gene symbol | PEDF |
| Gene ID (NCBI) | 5176 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Protein-A-Reinigung |
| Lagerungspuffer | PBS only |
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
PEDF also known as serpin F1 (SERPINF1), is a multifunctional secreted protein that has anti-angiogenic, anti-tumorigenic, and neurotrophic functionsis. It is an approximately 50-kDa secreted protein that is widely expressed, including by osteoblasts and osteoclasts. PEDF is also one of the most abundant secretory products of adipocytes, and circulating concentrations of PEDF correlate positively with body fat mass and INS resistance. PEDF is a neurotrophic factor involved in neuronal differentiation in retinoblastoma cells. Mutations in this gene were found in individuals with osteogenesis imperfecta, type VI.





