Serpin F1/PEDF Monoklonaler Antikörper

Serpin F1/PEDF Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

Hausschwein, human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

2C5C8

Kat-Nr. : 66554-1-PBS

Synonyme

PEDF, PIG35, 2C5C8, Cell proliferation-inducing gene 35 protein, EPC 1



Geprüfte Anwendungen

Produktinformation

66554-1-PBS bindet in WB, Indirect ELISA Serpin F1/PEDF und zeigt Reaktivität mit Hausschwein, human

Getestete Reaktivität Hausschwein, human
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen Serpin F1/PEDF fusion protein Ag26660
Vollständiger Name serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
Berechnetes Molekulargewicht 418 aa, 46 kDa
Beobachtetes Molekulargewicht 46-50 kDa
GenBank-ZugangsnummerBC013984
Gene symbol PEDF
Gene ID (NCBI) 5176
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

PEDF also known as serpin F1 (SERPINF1), is a multifunctional secreted protein that has anti-angiogenic, anti-tumorigenic, and neurotrophic functionsis. It is an approximately 50-kDa secreted protein that is widely expressed, including by osteoblasts and osteoclasts. PEDF is also one of the most abundant secretory products of adipocytes, and circulating concentrations of PEDF correlate positively with body fat mass and INS resistance. PEDF is a neurotrophic factor involved in neuronal differentiation in retinoblastoma cells. Mutations in this gene were found in individuals with osteogenesis imperfecta, type VI.