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PEG3 Polyklonaler Antikörper

PEG3 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 23569-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using PEG3 Polyclonal antibody (23569-1-AP)

    WB analysis using 23569-1-AP (same clone as 23569-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 23569-1-AP (PEG3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 23569-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human placenta tissue using PEG3 Polyclonal antibody (23569-1-AP)

    IHC staining of human placenta using 23569-1-AP (same clone as 23569-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 23569-1-AP (PEG3 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 23569-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse brain tissue using PEG3 Polyclonal antibody (23569-1-AP)

    IHC staining of mouse brain using 23569-1-AP (same clone as 23569-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 23569-1-AP (PEG3 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 23569-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human placenta tissue using PEG3 Polyclonal antibody (23569-1-AP)

    IHC staining of human placenta using 23569-1-AP (same clone as 23569-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 23569-1-AP (PEG3 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 23569-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

23569-1-PBS bindet in WB, IHC, Indirect ELISA PEG3 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen PEG3 fusion protein Ag20132
Vollständiger Name paternally expressed 3
Berechnetes Molekulargewicht 1588 aa, 181 kDa
Beobachtetes Molekulargewicht200-220 kDa
GenBank-ZugangsnummerBC150272
Gene symbol PEG3
Gene ID (NCBI) 5178
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-affinitätsgereinigt
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Paternally expressed 3 (PEG3) was responsible for Kras/Erk- and mTOR-driven HCC (hepatocellular carcinoma) (PMID: 36451866). PEG3 can regulate the physiological processes related to energy homeostasis found in multiple tissues, such as the brain, testis, ovary, and placenta (PMID: 32729618). Epigenetic silencing and loss of imprinting of PEG3 are implicated in glioma tumorigenesis (PMID: 32231463).