PEX1 Monoklonaler Antikörper

PEX1 Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG2b

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

2F3H5

Kat-Nr. : 67436-1-PBS

Synonyme

2F3H5, EC:3.6.4.-, Peroxin 1, Peroxin-1, Peroxisomal ATPase PEX1

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  WB analysis using 67436-1-Ig (same clone as 67436-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67436-1-Ig (PEX1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67436-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

67436-1-PBS bindet in WB, Indirect ELISA PEX1 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Maus / IgG2b
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: PEX1 fusion protein Ag4623
• Vollständiger Name: peroxisomal biogenesis factor 1
• Berechnetes Molekulargewicht: 1283 aa, 143 kDa
• Beobachtetes Molekulargewicht: 143 kDa
• GenBank-Zugangsnummer: BC035575
• Gene symbol: PEX1
• Gene ID (NCBI): 5189
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Peroxin (PEX) proteins generate and maintain peroxisomes. The peroxin-1 (PEX1) ATPase facilitates the recycling of the peroxisome matrix protein receptor PEX5 and is the most commonly affected peroxin in human peroxisome biogenesis disorders (PMID: 28600347).  PEX1 and PEX6 are the only members of the AAA family (for ATPases associated with diverse cellular) activities implicated in peroxisome biogenesis and are closely related to p97, which functions in endoplasmic reticulum-associated protein degradation to retrotranslocate endoplasmic reticulum proteins to the cytosol (PMID: 9695811; 11740563).