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PEX1 Rekombinanter Antikörper

PEX1 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

242994F11

Kat-Nr. : 85429-4-PBS

Synonyme

EC:3.6.4.-, Peroxin 1, Peroxin-1, Peroxisomal ATPase PEX1, Peroxisome biogenesis factor 1

Filter:
  • Western Blot (WB) analysis of various lysates using PEX1 Recombinant antibody (85429-4-RR)

    WB analysis using 85429-4-RR (same clone as 85429-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85429-4-RR (PEX1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85429-4-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 85429-4-RR

    Affinity and Kinetic Characterization of 85429-4-RR

    Biolayer interferometry (BLl) kinetic assays of 85429-4-RR against Human PEX1 were performed. The affinity constant is below 1 pM.

Geprüfte Anwendungen

Produktinformation

85429-4-PBS bindet in WB, Indirect ELISA PEX1 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen PEX1 fusion protein Ag4623
Vollständiger Name peroxisomal biogenesis factor 1
Berechnetes Molekulargewicht 1283 aa, 143 kDa
Beobachtetes Molekulargewicht143 kDa
GenBank-ZugangsnummerBC035575
Gene symbol PEX1
Gene ID (NCBI) 5189
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Peroxin (PEX) proteins generate and maintain peroxisomes. The peroxin-1 (PEX1) ATPase facilitates the recycling of the peroxisome matrix protein receptor PEX5 and is the most commonly affected peroxin in human peroxisome biogenesis disorders (PMID: 28600347).  PEX1 and PEX6 are the only members of the AAA family (for ATPases associated with diverse cellular) activities implicated in peroxisome biogenesis and are closely related to p97, which functions in endoplasmic reticulum-associated protein degradation to retrotranslocate endoplasmic reticulum proteins to the cytosol (PMID: 9695811; 11740563).