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PEX3 Polyklonaler Antikörper

PEX3 Polyklonal Antikörper für WB, IF-P, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IF-P, ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 10946-1-PBS

Synonyme

Peroxin 3, Peroxin-3, PEX

Filter:
  • Western Blot (WB) analysis of HeLa cells using PEX3 Polyclonal antibody (10946-1-AP)

    WB analysis of HeLa using 10946-1-AP (same clone as 10946-1-PBS)

    WB result of PEX3 antibody (10946-1-AP; 1:600; incubated at room temperature for 1.5 hours) with sh-Control and sh-PEX3 transfected HeLa cells. This data was developed using the same antibody clone with 10946-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of mouse brain tissue using PEX3 Polyclonal antibody (10946-1-AP)

    IF Staining of mouse brain using 10946-1-AP (same clone as 10946-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse brain tissue using PEX3 antibody (10946-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10946-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of mouse kidney tissue using PEX3 Polyclonal antibody (10946-1-AP)

    IF Staining of mouse kidney using 10946-1-AP (same clone as 10946-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse kidney tissue using PEX3 antibody (10946-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10946-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

10946-1-PBS bindet in WB, IF-P, ELISA PEX3 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen PEX3 fusion protein Ag1384
Vollständiger Name peroxisomal biogenesis factor 3
Berechnetes Molekulargewicht 42 kDa
Beobachtetes Molekulargewicht 42 kDa
GenBank-ZugangsnummerBC014551
Gene symbol PEX3
Gene ID (NCBI) 8504
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. Peroxin 3, also known as PEX3 (peroxisomal biogenesis factor 3) or TRG18, is a 373 amino acid multi-pass membrane protein that anchored in the peroxisomal membrane and essential for peroxisome biogenesis and integrity. Additionally, Peroxin 3 acts as a docking factor for Peroxin 19 and is required for the import of peroxisomal proteins. Defects in the gene encoding Peroxin 3 are the cause of peroxisome biogenesis disorder complementation group 12 (PBD-CG12) and Zellweger syndrome (ZwS), both of which arise from a failure of peroxisomal protein import.