PEX5 Monoklonaler Antikörper

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• KD/KO Validated

PEX5 Monoklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

Hausschwein, human, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

1C2C3

Kat-Nr. : 66309-1-PBS

Synonyme

Cell and organelle markers, Peroxin 5, Peroxisome Marker, Peroxisome receptor 1, PEX5, PTS1 BP, PTS1 receptor, PTS1R, PXR1

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  WB analysis of HEK-293 using 66309-1-Ig (same clone as 66309-1-PBS)

  WB result of PEX5 antibody (66309-1-Ig; 1:1000; incubated at room temperature for 1.5 hours) with sh-Control and sh-PEX5 transfected HEK-293 cells. This data was developed using the same antibody clone with 66309-1-PBS in a different storage buffer formulation.

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  WB analysis of pig brain using 66309-1-Ig (same clone as 66309-1-PBS)

  pig brain tissue were subjected to SDS PAGE followed by western blot with 66309-1-Ig (PEX5 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66309-1-PBS in a different storage buffer formulation.

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  WB analysis of fetal human brain using 66309-1-Ig (same clone as 66309-1-PBS)

  fetal human brain tissue were subjected to SDS PAGE followed by western blot with 66309-1-Ig (PEX5 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66309-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver using 66309-1-Ig (same clone as 66309-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 66309-1-Ig (PEX5 Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 66309-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver using 66309-1-Ig (same clone as 66309-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 66309-1-Ig (PEX5 Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 66309-1-PBS in a different storage buffer formulation.

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  IHC staining of human kidney using 66309-1-Ig (same clone as 66309-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 66309-1-Ig (PEX5 Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 66309-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human kidney using 66309-1-Ig (same clone as 66309-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 66309-1-Ig (PEX5 Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 66309-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

66309-1-PBS bindet in WB, IHC, Indirect ELISA PEX5 und zeigt Reaktivität mit Hausschwein, human, Ratten

• Getestete Reaktivität: Hausschwein, human, Ratte
• Wirt / Isotyp: Maus / IgG1
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: PEX5 fusion protein Ag3268
• Vollständiger Name: peroxisomal biogenesis factor 5
• Berechnetes Molekulargewicht: 631 aa, 70 kDa
• Beobachtetes Molekulargewicht: 70-80 kDa
• GenBank-Zugangsnummer: BC010621
• Gene symbol: PEX5
• Gene ID (NCBI): 5830
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-G-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The peroxisomal targeting signal type1 (PTS1) receptor, PEX5, is one member of peroxins (PEXs) which are proteins required for peroxisome assembly. PEX5 and PEX7 function as receptors that recognize PTS1- and PTS2- containing proteins, respectively, and PEX5 binds PTS1 through its C-terminal 40-kDa tetratricopeptide repeat domain. It is a predominantly cytoplasmic, partly peroxisomal protein that appears to shuttle between these compartments as it mediates the import of PTS1-containing proteins. PEX5 has been reported to interact with PEX10, PEX12, PEX13, and PEX14. Defects in PEX5 are a cause of Zellweger syndrome (ZWS), which is a lethal peroxisome biogenesis disorder.