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CXCL4/PF4 Rekombinanter Antikörper

CXCL4/PF4 Rekombinant Antikörper für WB, Cytometric bead array, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Cytometric bead array, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

242741H5

Kat-Nr. : 85738-1-PBS

Synonyme

C-X-C motif chemokine 4, CXCL4, PF-4, Platelet factor 4

Filter:
  • Western Blot (WB) analysis of various lysates using CXCL4/PF4 Recombinant antibody (85738-1-RR)

    WB analysis using 85738-1-RR (same clone as 85738-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85738-1-RR (CXCL4/PF4 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85738-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of human peripheral blood platelets using CXCL4/PF4 Recombinant antibody (85738-1-RR)

    WB analysis of human peripheral blood platelets using 85738-1-RR (same clone as 85738-1-PBS)

    human peripheral blood platelets were subjected to SDS PAGE followed by western blot with 85738-1-RR (PF4 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85738-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using CXCL4/PF4 Recombinant antibody (85738-1-RR)

    WB analysis using 85738-1-RR (same clone as 85738-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85738-1-RR (CXCL4/PF4 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85738-1-PBS in a different storage buffer formulation.

  • Cytometric bead array standard curve of MP02069-1

    Cytometric bead array standard curve of MP02069-1

    Cytometric bead array standard curve of MP02069-1, MOUSE CXCL4/PF4 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 85738-1-PBS. Detection antibody: 85738-2-PBS. Standard: Eg3345. Range: 0.781-100 ng/mL.

Geprüfte Anwendungen

Produktinformation

85738-1-PBS bindet in WB, Cytometric bead array, Indirect ELISA CXCL4/PF4 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen CXCL4/PF4 fusion protein Eg3345
Vollständiger Name platelet factor 4
Berechnetes Molekulargewicht11kd
Beobachtetes Molekulargewicht 10-14 kDa
GenBank-ZugangsnummerNM_019932
Gene symbol Pf4
Gene ID (NCBI) 56744
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The chemokine (C-X-C motif) ligand 4 (CXCL4) is also named as PF4 (Platelet factor-4) and SCYB4. The platelets, the most abundant source of CXCL4 in vivo, control profibrotic macrophage activation via CXCL4. (PMID: 36807143). Exogenous CXCL4 drove profibrotic activation of monocyte-derived dendritic cells in vitro (PMID: 33042127). Platelet factor-4 is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation.