PFDN4 Polyklonaler Antikörper

PFDN4 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 16045-1-PBS

Synonyme

---

• 

  WB analysis using 16045-1-AP (same clone as 16045-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 16045-1-AP (PFDN4 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16045-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 16045-1-AP (same clone as 16045-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 16045-1-AP (PFDN4 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 16045-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 16045-1-AP (same clone as 16045-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 16045-1-AP (PFDN4 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 16045-1-PBS in a different storage buffer formulation.

---

Geprüfte Anwendungen

Produktinformation

16045-1-PBS bindet in WB, IHC, Indirect ELISA PFDN4 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: PFDN4 fusion protein Ag8938
• Vollständiger Name: prefoldin subunit 4
• Berechnetes Molekulargewicht: 134 aa, 15 kDa
• Beobachtetes Molekulargewicht: 15-20 kDa
• GenBank-Zugangsnummer: BC010953
• Gene symbol: PFDN4
• Gene ID (NCBI): 5203
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The human PFDN4, prefoldin 4, is a subunit of the heterohexameric chaperone protein and belongs to the prefoldin family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. Previous reports have shown that PFDN4 is upregulated in breast cancer cell lines and tumor tissues (PMID: 11381030; PMID: 9630229). PFDN4 expression may be a prognostic factor in colorectal cancer (PMID: 20552408).