PFKFB2 Polyklonaler Antikörper

PFKFB2 Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 17838-1-PBS

Synonyme

Fructose-2,6-bisphosphatase, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2, 6-phosphofructo-2-kinase, 6PF-2-K/Fru-2,6-P2ase heart-type isozyme, 6PF-2-K/Fru-2,6-P2ase 2

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  WB analysis using 17838-1-AP (same clone as 17838-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 17838-1-AP (PFKFB2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17838-1-PBS in a different storage buffer formulation.

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  WB analysis of mouse retina using 17838-1-AP (same clone as 17838-1-PBS)

  mouse retina tissue were subjected to SDS PAGE followed by western blot with 17838-1-AP (PFKFB2 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17838-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

17838-1-PBS bindet in WB, ELISA PFKFB2 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: PFKFB2 fusion protein Ag12181
• Vollständiger Name: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
• Berechnetes Molekulargewicht: 505 aa, 58 kDa
• Beobachtetes Molekulargewicht: 55 kDa
• GenBank-Zugangsnummer: BC075076
• Gene symbol: PFKFB2
• Gene ID (NCBI): 5208
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

PFKFB2(6-Phosphofructo-2-kinase/fructose 2,6-bisphosphatase 2) is also named as PFK-2/FBPase-2, which is a bifunctional enzyme responsible for the synthesis and breakdown of Fru-2,6-P2 in the regulation of glycolysis(PMID:10095107). In the C-terminal section, it belongs to the phosphoglycerate mutase family. The enzyme is a dimer of identical subunits, each composed of 505 amino acids and containing three discrete domains(PMID: 2552438). It has 2 isoforms produced by alternative splicing.