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HPGDS Rekombinanter Antikörper

HPGDS Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

242980B8

Kat-Nr. : 85446-2-PBS

Synonyme

EC:2.5.1.18, EC:5.3.99.2, Glutathione S transferase, Glutathione S-transferase, Glutathione-dependent PGD synthase

Filter:
  • Western Blot (WB) analysis of human placenta tissue using HPGDS Recombinant antibody (85446-2-RR)

    WB analysis of human placenta using 85446-2-RR (same clone as 85446-2-PBS)

    human placenta tissue were subjected to SDS PAGE followed by western blot with 85446-2-RR (HPGDS antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85446-2-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 85446-2-RR

    Affinity and Kinetic Characterization of 85446-2-RR

    Biolayer interferometry (BLl) kinetic assays of 85446-2-RR against Human HPGDS were performed. The affinity constant is 0.168 nM.

Geprüfte Anwendungen

Produktinformation

85446-2-PBS bindet in WB, Indirect ELISA HPGDS und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen HPGDS fusion protein Ag18290
Vollständiger Name prostaglandin D2 synthase, hematopoietic
Berechnetes Molekulargewicht 199 aa, 23 kDa
Beobachtetes Molekulargewicht26 kDa, 52 kDa
GenBank-ZugangsnummerBC020734
Gene symbol HPGDS
Gene ID (NCBI) 27306
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Hematopoietic PGD synthase (HPGDS), one of the PGD2 synthases, is distributed in the cytoplasm of mast cells and Th2 cells and catalyzes PGD2 production during inflammation and allergic reactions. HPGDS belongs to the gene family of σ-type glutathione S-transferase (GST). Like other GSTs, it exists as a homodimer in vivo with a molecular weight of approximately 52 kDa (PMID: 38339125).