PHF2 Polyklonaler Antikörper

PHF2 Polyklonal Antikörper für WB, IHC, IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IHC, IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 24624-1-PBS

Synonyme

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  WB analysis of Jurkat using 24624-1-AP (same clone as 24624-1-PBS)

  Jurkat cells were subjected to SDS PAGE followed by western blot with 24624-1-AP (PHF2 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24624-1-PBS in a different storage buffer formulation.

• 

  IP experiment of HeLa using 24624-1-AP (same clone as 24624-1-PBS)

  IP result of anti-PHF2 (IP:24624-1-AP, 4ug; Detection:24624-1-AP 1:500) with HeLa cells lysate 1800ug. This data was developed using the same antibody clone with 24624-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human cervical cancer using 24624-1-AP (same clone as 24624-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue slide using 24624-1-AP (PHF2 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 24624-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human cervical cancer using 24624-1-AP (same clone as 24624-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue slide using 24624-1-AP (PHF2 Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 24624-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

24624-1-PBS bindet in WB, IHC, IP, Indirect ELISA PHF2 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: PHF2 fusion protein Ag20257
• Vollständiger Name: PHD finger protein 2
• Berechnetes Molekulargewicht: 1101 aa, 121 kDa
• Beobachtetes Molekulargewicht: 150 kDa
• GenBank-Zugangsnummer: BC152437
• Gene symbol: PHF2
• Gene ID (NCBI): 5253
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

PHD finger protein 2 (PHF2), also known as JHDM1E (Jumonji C domain-containing histone demethylase 1E) or GRC5, is a 1101 amino acid protein, which contains one JmjC domain and one PHD-type zinc finger. PHF2 belongs to the JHDM1 histone demethylase family and localizes in the nucleus. PHF2 demethylases both histones and non-histione proteins. PHF2 is widely expressed in various tissues and exists as two alternative splicing isoforms. The gene encoding PHF2 lies in the candidate region for hereditary sensory neuropathy type I (HSN1), a disorder characterized by sensory dysfunction