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PHLPP1 Monoklonaler Antikörper

PHLPP1 Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG2b

Getestete Reaktivität

Hausschwein, human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

2E8E6

Kat-Nr. : 67640-1-PBS

Synonyme

PLEKHE1, 2E8E6, EC:3.1.3.16, hSCOP, KIAA0606

Filter:
  • Western Blot (WB) analysis of mouse brain tissue using PHLPP1 Monoclonal antibody (67640-1-Ig)

    WB analysis of mouse brain using 67640-1-Ig (same clone as 67640-1-PBS)

    mouse brain tissue were subjected to SDS PAGE followed by western blot with 67640-1-Ig (PHLPP1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67640-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of rat brain tissue using PHLPP1 Monoclonal antibody (67640-1-Ig)

    WB analysis of rat brain using 67640-1-Ig (same clone as 67640-1-PBS)

    rat brain tissue were subjected to SDS PAGE followed by western blot with 67640-1-Ig (PHLPP1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67640-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of pig brain tissue using PHLPP1 Monoclonal antibody (67640-1-Ig)

    WB analysis of pig brain using 67640-1-Ig (same clone as 67640-1-PBS)

    pig brain tissue were subjected to SDS PAGE followed by western blot with 67640-1-Ig (PHLPP1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67640-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of HEK-293 cells using PHLPP1 Monoclonal antibody (67640-1-Ig)

    WB analysis of HEK-293 using 67640-1-Ig (same clone as 67640-1-PBS)

    HEK-293 cells were subjected to SDS PAGE followed by western blot with 67640-1-Ig (PHLPP1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67640-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

67640-1-PBS bindet in WB, Indirect ELISA PHLPP1 und zeigt Reaktivität mit Hausschwein, human, Maus, Ratten

Getestete Reaktivität Hausschwein, human, Maus, Ratte
Wirt / Isotyp Maus / IgG2b
Klonalität Monoklonal
Typ Antikörper
Immunogen PHLPP1 fusion protein Ag18982
Vollständiger Name PH domain and leucine rich repeat protein phosphatase
Berechnetes Molekulargewicht 1717 aa, 184 kDa
Beobachtetes Molekulargewicht 185 kDa
GenBank-ZugangsnummerBC126277
Gene symbol PHLPP
Gene ID (NCBI) 23239
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

PHLPP (PH domain leucine-rich-repeats protein phosphatase) belongs to a novel family of Ser/Thr protein phosphatases that consists of PHLPP1 and PHLPP2 isoforms. It has been shown that PHLPP negatively regulates multiple oncogenic pathways by directly dephosphorylating and inactivating key signaling molecules, including Akt, S6K, and RAF1. Observed MW of PHLPP1 beta is 185 kDa.