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PI3 Kinase p110 Alpha Rekombinanter Antikörper

PI3 Kinase p110 Alpha Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

1B4

Kat-Nr. : 82796-4-PBS

Synonyme

PI3K p110(alpha), PIK3CA, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha, p110 alpha

Filter:
  • Western Blot (WB) analysis of various lysates using PI3 Kinase p110 Alpha Recombinant antibody (82796-4-RR)

    WB analysis using 82796-4-RR (same clone as 82796-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 82796-4-RR (PIK3CA antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82796-4-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 82796-4-RR

    Affinity and Kinetic Characterization of 82796-4-RR

    Biolayer interferometry (BLl) kinetic assays of 82796-4-RR against Human PI3 Kinase p110 Alpha were performed. The affinity constant is 0.639 nM.

Geprüfte Anwendungen

Produktinformation

82796-4-PBS bindet in WB, Indirect ELISA PI3 Kinase p110 Alpha und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen PI3 Kinase p110 Alpha fusion protein Ag16586
Vollständiger Name phosphoinositide-3-kinase, catalytic, alpha polypeptide
Berechnetes Molekulargewicht 1068 aa, 124 kDa
Beobachtetes Molekulargewicht110 kDa
GenBank-ZugangsnummerBC113601
Gene symbol PIK3CA
Gene ID (NCBI) 5290
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

PIK3CA belongs to the PI3/PI4-kinase family. It phosphorylates PtdIns, PtdIns4P and PtdIns(4,5)P2 with a preference for PtdIns(4,5)P2. Defects in PIK3CA are associated with colorectal cancer (CRC). Defects in PIK3CA are associated with breast cancer. Defects in PIK3CA are associated with ovarian cancer. Defects in PIK3CA may underlie hepatocellular carcinoma (HCC). Defects in PIK3CA are a cause of keratosis seborrheic (KERSEB).