PITX2 Monoklonaler Antikörper

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• KD/KO Validated

PITX2 Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

1E3B1

Kat-Nr. : 67201-1-PBS

Synonyme

1E3B1, ALL1-responsive protein ARP1, ARP1, Paired-like homeodomain transcription factor 2, RIEG bicoid-related homeobox transcription factor

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  WB analysis using 67201-1-Ig (same clone as 67201-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67201-1-Ig (PITX2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated Beta Actin Monoclonal antibody (HRP-66009) as loading control. This data was developed using the same antibody clone with 67201-1-PBS in a different storage buffer formulation.

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  WB analysis of HEK-293 using 67201-1-Ig (same clone as 67201-1-PBS)

  HEK-293 cells were subjected to SDS PAGE followed by western blot with 67201-1-Ig (PITX2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67201-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

67201-1-PBS bindet in WB, Indirect ELISA PITX2 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Maus / IgG1
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: PITX2 fusion protein Ag27924
• Vollständiger Name: paired-like homeodomain 2
• Berechnetes Molekulargewicht: 36 kDa
• Beobachtetes Molekulargewicht: 30 kDa
• GenBank-Zugangsnummer: BC013998
• Gene symbol: PITX2
• Gene ID (NCBI): 5308
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

PITX2 belongs to the bicoid class of homeodomain transcription factors, which play essential roles in embryonic development. Various PITX2 isoforms are involved in a wide variety of developmental programs, including left-right signaling. It controls cell proliferation in a tissue-specific manner and is involved in morphogenesis. During embryonic development, PITX2 is involved in the expansion of muscle progenitors. In addition, it may play a role in the proper localization of asymmetric organs such as the heart and stomach. PITX2 can be bound by some other proteins, and are part of a much larger atrial transcriptional complex. This antibody specifically recognizes isoform PTX2C.