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PLCB3 Rekombinanter Antikörper

PLCB3 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

243045B8

Kat-Nr. : 85786-1-PBS

Synonyme

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3, EC:3.1.4.11, Phosphoinositide phospholipase C-beta-3, Phospholipase C beta 3, Phospholipase C-beta-3

Filter:
  • Western Blot (WB) analysis of various lysates using PLCB3 Recombinant antibody (85786-1-RR)

    WB analysis using 85786-1-RR (same clone as 85786-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85786-1-RR (PLCB3 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85786-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

85786-1-PBS bindet in WB, Indirect ELISA PLCB3 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Peptid
Vollständiger Name phospholipase C, beta 3 (phosphatidylinositol-specific)
Berechnetes Molekulargewicht 1234 aa, 139 kDa
Beobachtetes Molekulargewicht 139-150 kDa
GenBank-ZugangsnummerBC142681
Gene symbol PLCB3
Gene ID (NCBI) 5331
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

PLCB3 is a member of the phosphoinositide phospholipase C beta enzyme family that catalyze the production of the secondary messengers diacylglycerol and inositol 1,4,5-triphosphate from phosphatidylinositol in G-protein-linked receptor-mediated signal transduction. Six subfamilies of PLCs (B, G, D, E, Z and H) constitute part of ubiquitous signaling cascades that translate hormonal signals into intracellular events, leading to alternations in cell function. PLCB isoforms 1-4 are stimulated by G-protein activation (Gαq/11 and/or Gβγ). Independent of its enzymatic activity, PLCB3 inhibits the proliferation of hematopoietic stem cells (HSCs) and myeloid cells.