• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

Perilipin 1 Rekombinanter Antikörper

Perilipin 1 Rekombinant Antikörper für WB, IP, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IP, ELISA

Konjugation

Unkonjugiert

CloneNo.

240994H1

Kat-Nr. : 83905-4-PBS

Synonyme

PLIN, 240994H1, PERI, PLIN1

Filter:
  • Western Blot (WB) analysis of various lysates using Perilipin 1 Recombinant antibody (83905-4-RR)

    WB analysis using 83905-4-RR (same clone as 83905-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 83905-4-RR (PLIN1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83905-4-PBS in a different storage buffer formulation.

  • Immunoprecipitation (IP) experiment of MCF-7 cells using Perilipin 1 Recombinant antibody (83905-4-RR)

    IP experiment of MCF-7 using 83905-4-RR (same clone as 83905-4-PBS)

    IP result of anti-Perilipin 1 (IP:83905-4-RR, 4ug; Detection:83905-4-RR 1:4000) with MCF-7 cells lysate 1240 ug. This data was developed using the same antibody clone with 83905-4-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 83905-4-RR

    Affinity and Kinetic Characterization of 83905-4-RR

    Biolayer interferometry (BLl) kinetic assays of 83905-4-RR against Human Perilipin 1 were performed. The affinity constant is 0.617 nM.

Geprüfte Anwendungen

Produktinformation

83905-4-PBS bindet in WB, IP, ELISA Perilipin 1 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Perilipin 1 fusion protein Ag26426
Vollständiger Name perilipin
Berechnetes Molekulargewicht 56 kDa
Beobachtetes Molekulargewicht67 kDa
GenBank-ZugangsnummerNM_001145311
Gene symbol Perilipin 1
Gene ID (NCBI) 5346
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

PLIN1, also known as Perilipin 1, PLIN, PERI, belongs to the perilipin family. PLIN1 is a hormonally-regulated phosphoprotein that encircles the lipid storage droplet in adipocytes and modulates adipocyte lipid metabolism (PMID: 2040638). PLIN1 is the major cAMP-dependent protein kinase substrate in adipocytes and, when unphosphorylated, may play a role in inhibiting lipolysis. PLIN1 is detected in adipocytes of white adipose tissue, visceral adipose tissue, and mammary gland (PMID: 27832861, 9521880). The deficiency of PLIN1 causes lipodystrophic syndromes, which disables the optimal accumulation of triglycerides in adipocytes that results in abnormal deposition of lipids in tissues such as skeletal muscle and liver. The storage of lipids in the liver leads to insulin resistance and hypertriglyceridemia (PMID: 21345103).