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PLSCR1 Rekombinanter Antikörper

PLSCR1 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

242372B2

Kat-Nr. : 84888-4-PBS

Synonyme

phospholipid scramblase 1, MMTRA1B, Mg(2+)-dependent nuclease, EC:3.1.-.-, Ca(2+)-dependent phospholipid scramblase 1

Filter:
  • Western Blot (WB) analysis of various lysates using PLSCR1 Recombinant antibody (84888-4-RR)

    WB analysis using 84888-4-RR (same clone as 84888-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84888-4-RR (PLSCR1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84888-4-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84888-4-RR

    Affinity and Kinetic Characterization of 84888-4-RR

    Biolayer interferometry (BLl) kinetic assays of 84888-4-RR against Human PLSCR1 were performed. The affinity constant is 0.377 nM.

Geprüfte Anwendungen

Produktinformation

84888-4-PBS bindet in WB, Indirect ELISA PLSCR1 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen PLSCR1 fusion protein Ag2172
Vollständiger Name phospholipid scramblase 1
Berechnetes Molekulargewicht 318 aa, 35 kDa
Beobachtetes Molekulargewicht34 kDa
GenBank-ZugangsnummerBC021100
Gene symbol PLSCR1
Gene ID (NCBI) 5359
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

PLSCR1 (Phospholipid scramblase 1) is a member of the family of membrane proteins that mediate the transbilayer movement of phospholipids ("scrambling") in a Ca2+ dependent manner, which was identified as an a type II transmembrane protein involved in the calcium-dependent, nonspecific, rapid redistribution of phospholipids. A cysteine-rich palmitoylation motif [184CCCPCC189] of PLSCR1, a thioester linkage to the sulfhydryl groups of cysteines, controls the transportation of PLSCR1 to the cell membrane or nucleus (PMID: 32292520). PLSCR1 is strongly expressed in response to interferon (IFN) treatment and viral infection (PMID: 35138119, 23487022).