• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

PLVAP Rekombinanter Antikörper

PLVAP Rekombinant Antikörper für FC

Wirt / Isotyp

Ratte / IgG2a

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

MECA-32

Kat-Nr. : 65664-1-PBS

Synonyme

MECA32, MECA-32, Panendothelial cell antigen, Plasmalemma vesicle protein 1, PV 1

Filter:
  • Flow cytometry (FC) experiment of bEnd.3 cells using Anti-Mouse PLVAP (MECA-32) Rat IgG2a Recombinant A (65664-1-TR)

    FC experiment of bEnd.3 using 65664-1-TR (same clone as 65664-1-PBS)

    1x10^6 bEnd.3 cells were surface stained with 0.25 ug Anti-Mouse PLVAP (MECA-32) Rat IgG2a RecAb (65664-1-TR, Clone:MECA-32) (red) or 0.25 ug Rat IgG2a Isotype Control (2A3) (65209-1-Ig, Clone: 2A3) (blue), and FITC anti-Rat IgG2a antibody. Cells were not fixed. This data was developed using the same antibody clone with 65664-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

65664-1-PBS bindet in FC PLVAP und zeigt Reaktivität mit Maus

Getestete Reaktivität Maus
Wirt / Isotyp Ratte / IgG2a
Klonalität Rekombinant
Typ Antikörper
Immunogen k.A.
Vollständiger Name plasmalemma vesicle associated protein
GenBank-ZugangsnummerBC013517
Gene symbol Plvap
Gene ID (NCBI) 84094
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C.

Hintergrundinformationen

Plasmalemma vesicle-associated protein (PLVAP), also known as PV-1, PAL-E and MECA-32 antigen, is an endothelial cell-specific type II membrane N-glycosylated glycoprotein with a molecular weight of approximately 50-65 kDa, that forms homodimers in situ (PMID: 7626790; 30231925). The MECA-32 antibody, derived from rats immunized with murine lymph node stroma, shows high specificity for mouse endothelium in both embryonic and mature tissues (PMID: 2683264; 7626790). It recognizes most endothelial cells in the embryonic and in the adult mouse, with the exception of the brain, skeletal, and cardiac muscle, where the MECA-32 antigen has a more restricted distribution. In skeletal and cardiac muscle only small arterioles and venules express the MECA-32 antigen, while in the brain its expression is negatively correlated with the differentiation of the vasculature to form the blood brain barrier (PMID: 7626790).