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PLXNA4 Polyklonaler Antikörper

PLXNA4 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 17201-1-PBS

Synonyme

FAYV2820, KIAA1550, PLEXA4, plexin A4, Plexin-A4

Filter:
  • Western Blot (WB) analysis of various lysates using PLXNA4 Polyclonal antibody (17201-1-AP)

    WB analysis using 17201-1-AP (same clone as 17201-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 17201-1-AP (PLXNA4 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17201-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

17201-1-PBS bindet in WB, Indirect ELISA PLXNA4 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen PLXNA4 fusion protein Ag10978
Vollständiger Name plexin A4
Berechnetes Molekulargewicht522aa,58 kDa; 1894aa,212 kDa
Beobachtetes Molekulargewicht212 kDa
GenBank-ZugangsnummerBC028744
Gene symbol PLXNA4
Gene ID (NCBI) 91584
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

PLXNA4 is a plexin family receptor that transduces semaphorin signals to regulate axon guidance, vascular development, and immune cell migration. It functions as a plasma membrane receptor with intracellular GTPase-regulatory activity, linking extracellular cues to cytoskeletal remodeling. Dysregulation of PLXNA4 has been associated with neurological disease (including Alzheimer's), cancer progression, and vascular/immune dysfunction, making it a multifunctional receptor of significant biomedical interest. (PMID: 27127761)