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PMP2 Polyklonaler Antikörper

PMP2 Polyklonal Antikörper für WB, IHC, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Hausschwein, human, Maus, Ratte

Anwendung

WB, IHC, IF, ELISA

Konjugation

Unkonjugiert

Publikationen(19)

Kat-Nr. : 12717-1-AP

Synonyme

FABP8, M FABP, MP2, Myelin P2 protein, P2, peripheral myelin protein 2, PMP2



Geprüfte Anwendungen

Erfolgreiche Detektion in WBHausschwein-Rückenmarkgewebe, humanes Hirngewebe, Maushodengewebe
Erfolgreiche Detektion in IHChumanes Gliomgewebe
Hinweis: Antigendemaskierung mit TE-Puffer pH 9,0 empfohlen. (*) Wahlweise kann die Antigendemaskierung auch mit Citratpuffer pH 6,0 erfolgen.

Empfohlene Verdünnung

AnwendungVerdünnung
Western Blot (WB)WB : 1:500-1:2000
Immunhistochemie (IHC)IHC : 1:20-1:200
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

12717-1-AP bindet in WB, IHC, IF, ELISA PMP2 und zeigt Reaktivität mit Hausschwein, human, Maus, Ratten

Getestete Reaktivität Hausschwein, human, Maus, Ratte
In Publikationen genannte Reaktivitäthuman, Hausschwein, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen PMP2 fusion protein Ag3411
Vollständiger Name peripheral myelin protein 2
Berechnetes Molekulargewicht 132 aa, 15 kDa
Beobachtetes Molekulargewicht 15-20 kDa
GenBank-ZugangsnummerBC034997
Gene symbol PMP2
Gene ID (NCBI) 5375
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS with 0.02% sodium azide and 50% glycerol
LagerungsbedingungenBei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

PMP2 (peripheral myelin protein-2, also known as P2) is one of the major proteins of peripheral myelin and appears to be related to the transport of fatty acids or the metabolism of myelin lipids.P2 constitutes up to 15% of total protein of peripheral nervous system (PNS) myelin. It is also present in small amounts in central nervous system (CNS) myelin, being abundant in spinal cord and brain stem myelin. As a structural protein, P2 is thought to stabilize the myelin membranes.

Protokolle

PRODUKTSPEZIFISCHE PROTOKOLLE
WB protocol for PMP2 antibody 12717-1-APProtokoll herunterladen
IHC protocol for PMP2 antibody 12717-1-APProtokoll herunterladenl
STANDARD-PROTOKOLLE
Klicken Sie hier, um unsere Standardprotokolle anzuzeigen

Publikationen

SpeciesApplicationTitle
humanIHC

Nat Neurosci

Variation among intact tissue samples reveals the core transcriptional features of human CNS cell classes.

Authors - Kevin W Kelley
mouseIHC

Nat Neurosci

Disentangling glial diversity in peripheral nerves at single-nuclei resolution.

Authors - Aldrin K Y Yim

Neuron

Molecular pathways and diagnosis in spatially resolved Alzheimer's hippocampal atlas

Authors - Pan Wang
pigWB

Neuron

Macrophages Expressing GALC Improve Peripheral Krabbe Disease by a Mechanism Independent of Cross-Correction.

Authors - Nadav I Weinstock
mouseWB

J Cell Biol

Fatty acid-binding proteins 3, 7, and 8 bind cholesterol and facilitate its egress from lysosomes

Authors - Xian-Xiu Fang
  • KD Validated
mouseWB

Elife

Proteome profile of peripheral myelin in healthy mice and in a neuropathy model.

Authors - Sophie B Siems

Rezensionen

The reviews below have been submitted by verified Proteintech customers who received an incentive for providing their feedback.


FH

Samantha (Verified Customer) (08-29-2025)

This antibody was used in a Western Blot and detected PMP2 in human sciatic nerve and bound to myelin recombinant protein

  • Applications: Western Blot
  • Primary Antibody Dilution: 1 in 500
  • Cell Tissue Type: N/A