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POLG Polyklonaler Antikörper

POLG Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 14110-1-PBS

Synonyme

EC:4.2.99.-, EC:3.1.11.-, EC:2.7.7.7, DNA polymerase subunit gamma-1, 5'-deoxyribose-phosphate lyase

Filter:
  • Western Blot (WB) analysis of various lysates using POLG Polyclonal antibody (14110-1-AP)

    WB analysis using 14110-1-AP (same clone as 14110-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 14110-1-AP (POLG antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14110-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

14110-1-PBS bindet in WB, Indirect ELISA POLG und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen POLG fusion protein Ag5256
Vollständiger Name polymerase (DNA directed), gamma
Berechnetes Molekulargewicht 140 kDa
Beobachtetes Molekulargewicht 130-150 kDa
GenBank-ZugangsnummerBC042571
Gene symbol POLG
Gene ID (NCBI) 5428
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

POLG is the catalytic subunit of DNA polymerase gamma solely responsible for the replication of mitochondrial DNA (mtDNA). POLG replicates both heavy and light strands of the circular mtDNA genome using a single-stranded DNA template, RNA primers, and the four deoxyribonucleoside triphosphates as substrates (PMID:11477093; 11897778; 15917273; 19837034; 9558343).