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PON2 Rekombinanter Antikörper

PON2 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

251083G7

Kat-Nr. : 86347-3-PBS

Synonyme

A-esterase 2, Aromatic esterase 2, EC:3.1.1.2, paraoxonase 2, Serum aryldialkylphosphatase 2

Filter:
  • Western Blot (WB) analysis of various lysates using PON2 Recombinant antibody (86347-3-RR)

    WB analysis using 86347-3-RR (same clone as 86347-3-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86347-3-RR (PON2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86347-3-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 86347-3-RR

    Affinity and Kinetic Characterization of 86347-3-RR

    Biolayer interferometry (BLl) kinetic assays of 86347-3-RR against Human PON2 were performed. The affinity constant is below 1 pM.

Geprüfte Anwendungen

Produktinformation

86347-3-PBS bindet in WB, Indirect ELISA PON2 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen PON2 fusion protein Ag5759
Vollständiger Name paraoxonase 2
Berechnetes Molekulargewicht 39 kDa
Beobachtetes Molekulargewicht 37~39 kDa
GenBank-ZugangsnummerBC046160
Gene symbol PON2
Gene ID (NCBI) 5445
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

PON2(Serum paraoxonase/arylesterase 2) has antioxidant activity and can prevents LDL lipid peroxidation, reverses the oxidation of mildly oxidized LDL, and inhibits the ability of MM-LDL to induce monocyte chemotaxis. Highest levels of PON2 protein are found in the mouse lung and small intestine, followed by the heart and liver, while lower levels are present in the testis, kidney and brain. PON2 expression in tissues from female mice is always significantly higher than in male animals. There are also some reports showing two bands of 43 kDa and 53 kDa to be detected through western blot as the two isoforms of this protein. (PMID:21354197).